thrazarine

Modify Date: 2024-03-03 15:41:08

thrazarine Structure
thrazarine structure
Common Name thrazarine
CAS Number 120128-14-5 Molecular Weight 217.17900
Density N/A Boiling Point N/A
Molecular Formula C7H11N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of thrazarine


Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].

 Names

Name (Z,3R)-1-[(2S)-2-amino-2-carboxyethoxy]-2-diazonio-3-hydroxybut-1-en-1-olate
Synonym More Synonyms

 thrazarine Biological Activity

Description Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].
Related Catalog
References

[1]. Kameyama T, et al. Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo). 1988 Nov;41(11):1561-7.  

 Chemical & Physical Properties

Molecular Formula C7H11N3O5
Molecular Weight 217.17900
Exact Mass 217.07000
PSA 143.99000

 Synonyms

Thrazarine
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