BMN-673 (8R,9S)

Modify Date: 2024-01-02 10:30:22

BMN-673 (8R,9S) structure	Common Name	BMN-673 (8R,9S)
	CAS Number	1207456-00-5	Molecular Weight	380.35100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₄F₂N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BMN-673 (8R,9S)

Talazoparib 8R,9S (BMN-673 8R,9S) is an enantiomer of Talazoparib, less active than Talazoparib on the inhibition of PARP1, with an IC50 of 144 nM.

Name	(8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3 ,2-de] phthalazin-3(7H)-one
Synonym	More Synonyms

Description	Talazoparib 8R,9S (BMN-673 8R,9S) is an enantiomer of Talazoparib, less active than Talazoparib on the inhibition of PARP1, with an IC50 of 144 nM.
Related Catalog	Research Areas >> Cancer
Target	PARP-1:144 nM (IC50)
References	[1]. Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-

Molecular Formula	C₁₉H₁₄F₂N₆O
Molecular Weight	380.35100
Exact Mass	380.12000
PSA	91.98000
LogP	1.89830

Precursor 7
CAS#:1207454-56-5 BMN 673 CAS#:1207453-90-4 6-Fluoro-4-nitr... CAS#:1322616-34-1 1(3H)-Isobenzof... CAS#:459-57-4 4-Fluorobenzaldehyde
CAS#:1322879-81-1 methyl 5-fluoro... CAS#:1322616-36-3 5-Quinolinecarb... CAS#:1322616-40-9 methyl 7-fluoro...
DownStream 0

(8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one

BMN-673 8R,9S||BMN673 (8R,9S)|BMN 673 (8R,9S)

BMN 673 (8R,9S)

CS-1223

BMN-673 (8R,9S)

DC Chemicals Limited
China
Product Name: BMN-673 8R,9S
Price: $600.0/100mg $1100.0/250mg $2100.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: BMN 673 (8R,9S)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $198/10mM*1mLinDMSO

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