ML202

Modify Date: 2024-03-03 20:26:02

ML202 Structure
ML202 structure
Common Name ML202
CAS Number 1221186-52-2 Molecular Weight 387.47600
Density N/A Boiling Point N/A
Molecular Formula C18H17N3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ML202


ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect[1].

 Names

Name 2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone

 ML202 Biological Activity

Description ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect[1].
Related Catalog
References

[1]. Matthew B Boxer, et al. Identification of activators for the M2 isoform of human pyruvate kinase Version 3. 2009 Sep 1 [updated 2011 Mar 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.   

 Chemical & Physical Properties

Molecular Formula C18H17N3O3S2
Molecular Weight 387.47600
Exact Mass 387.07100
PSA 113.57000
LogP 3.60970
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  • DC Chemicals Limited
  • China
  • Product Name: ML202
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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