TC-I 2014

Modify Date: 2024-01-13 17:03:07

TC-I 2014 structure	Common Name	TC-I 2014
	CAS Number	1221349-53-6	Molecular Weight	467.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₉F₆N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TC-I 2014

TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1].

Name	TC-I 2014

Description	TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	TRPM8[1].
References	[1]. Parks DJ, et Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists. J Med Chem. 2011 Jan 13;54(1):233-47.

Molecular Formula	C₂₃H₁₉F₆N₃O
Molecular Weight	467.41

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TC-I 2014
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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Chemical & Physical Properties