CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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GD0300400
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CHEMICAL NAME :
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C.I. Fluorescent Brightening Agent 24
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CAS REGISTRY NUMBER :
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12224-02-1
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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10
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MOLECULAR FORMULA :
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C40-H40-N12-O16-S4.4Na
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MOLECULAR WEIGHT :
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1165.12
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WISWESSER LINE NOTATION :
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T6N CN ENJ BN2Q2Q DMR DSWO FMR CSWO D1U1R BSWO DM- BT6N CN ENJ DN2Q2Q FMR CSWO &-NA- 4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973 ** ACUTE TOXICITY DATA **
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1960 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1750 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1620 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1500 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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900 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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13800 mg/kg/30D-I
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TOXIC EFFECTS :
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Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired Blood - change in clotting factors
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),88,1986
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