JW-7-25-1

Modify Date: 2025-08-25 12:41:28

JW-7-25-1 Structure
JW-7-25-1 structure
 Common Name JW-7-25-1
CAS Number 1222998-57-3 Molecular Weight 516.524
Density N/A Boiling Point N/A
Molecular Formula C29H23F3N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JW-7-25-1


JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM; exhibits a broad kinase selectivity profile with an S(35) score of 0.54 at 10 uM.

 Names

Name JW-7-25-1

 JW-7-25-1 Biological Activity

Description JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM; exhibits a broad kinase selectivity profile with an S(35) score of 0.54 at 10 uM.
References References 1. Huang HT, et al. Elife. 2017 Sep 19;6. pii: e26693. View Related Products by Target MELK

 Chemical & Physical Properties

Molecular Formula C29H23F3N4O2
Molecular Weight 516.524
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Chemsrc provides JW-7-25-1(CAS#:1222998-57-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of JW-7-25-1 are included as well.>> amp version: JW-7-25-1

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