L-663581

Modify Date: 2025-08-27 00:38:49

L-663581 Structure
L-663581 structure
 Common Name L-663581
CAS Number 122384-14-9 Molecular Weight 357.79400
Density 1.5g/cm3 Boiling Point 624.1ºC at 760mmHg
Molecular Formula C17H16ClN5O2 Melting Point N/A
MSDS N/A Flash Point 331.3ºC

 Use of L-663581


L-663581 (FG-8205) is an agonist of benzodiazepine receptor, acting as a partial agonist at GABA A receptor[1].

 Names

Name 7-chloro-5-methyl-3-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5g/cm3
Boiling Point 624.1ºC at 760mmHg
Molecular Formula C17H16ClN5O2
Molecular Weight 357.79400
Flash Point 331.3ºC
Exact Mass 357.09900
PSA 77.05000
LogP 3.22260
Vapour Pressure 1.7E-15mmHg at 25°C
Index of Refraction 1.719

 Synthetic Route

7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carbonitrile structure

7-chloro-5,6-di...

CAS#:106937-66-0

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L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
N/A structure

N/A

CAS#:99622-53-4

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid structure

7-chloro-5,6-di...

CAS#:84378-33-6

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
Formamide, N-[[5-(1-methylethyl)-1,2,4-oxadiazol-3-yl]methyl]- (9CI) structure

Formamide, N-[[...

CAS#:122384-65-0

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
3-(isocyanomethyl)-5-propan-2-yl-1,2,4-oxadiazole structure

3-(isocyanometh...

CAS#:122384-66-1

3,4-dihydro-4-methyl-6-chloro-2H-1,4-benzodiazepine-2,5(1H)-dione structure

3,4-dihydro-4-m...

CAS#:78755-99-4

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
Sarmazenil structure

Sarmazenil

CAS#:78771-13-8

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291
3,4-dihydro-4-methyl-6-chloro-2H-1,4-benzodiazepine-2,5(1H)-dione structure

3,4-dihydro-4-m...

CAS#:78755-99-4

~%

L-663581 Structure

L-663581

CAS#:122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

 Synonyms

[14C]-FG 8205
7-chloro-5,6-dihydro-3-(5-isopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo<1,5-a><1,4>benzodiazepine
FG 8205
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Chemsrc provides L-663581(CAS#:122384-14-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of L-663581 are included as well.>> amp version: L-663581

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