2-Chloro-3’-deoxy-3’-fluoroadenosine

Modify Date: 2024-02-08 11:09:11

2-Chloro-3’-deoxy-3’-fluoroadenosine Structure
2-Chloro-3’-deoxy-3’-fluoroadenosine structure
Common Name 2-Chloro-3’-deoxy-3’-fluoroadenosine
CAS Number 122654-30-2 Molecular Weight 303.68
Density 2.1±0.1 g/cm3 Boiling Point 550.0±60.0 °C at 760 mmHg
Molecular Formula C10H11ClFN5O3 Melting Point N/A
MSDS N/A Flash Point 286.4±32.9 °C

 Use of 2-Chloro-3’-deoxy-3’-fluoroadenosine


2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Deoxy-3'-fluoro-2-chloroadenosine
Synonym More Synonyms

 2-Chloro-3’-deoxy-3’-fluoroadenosine Biological Activity

Description 2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.1±0.1 g/cm3
Boiling Point 550.0±60.0 °C at 760 mmHg
Molecular Formula C10H11ClFN5O3
Molecular Weight 303.68
Flash Point 286.4±32.9 °C
Exact Mass 303.053436
LogP 0.71
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.844

 Synonyms

2-Chloro-3'-deoxy-3'-fluoroadenosine
Adenosine, 2-chloro-3'-deoxy-3'-fluoro-