L-Tyrosine-d5

Modify Date: 2024-02-14 13:28:44

L-Tyrosine-d5 Structure
L-Tyrosine-d5 structure
 Common Name L-Tyrosine-d5
CAS Number 1226919-57-8 Molecular Weight 186.22
Density N/A Boiling Point N/A
Molecular Formula C9H6D5NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Tyrosine-d5


L-Tyrosine-d5 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

 Names

Name L-4-Hydroxyphenyl-d4-alanine-d1

 L-Tyrosine-d5 Biological Activity

Description L-Tyrosine-d5 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Ferreira GK, et al. Effect of L-tyrosine in vitro and in vivo on energy metabolism parameters in brain and liver of young rats. Neurotox Res. 2013 May;23(4):327-35.

 Chemical & Physical Properties

Molecular Formula C9H6D5NO3
Molecular Weight 186.22
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