2'-Fluorothymidine

Modify Date: 2025-10-29 21:52:52

2'-Fluorothymidine Structure
2'-Fluorothymidine structure
Common Name 2'-Fluorothymidine
CAS Number 122799-38-6 Molecular Weight 260.219
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Fluorothymidine


2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].

 Names

Name 2'-deoxy-2'-fluorothymidine
Synonym More Synonyms

 2'-Fluorothymidine Biological Activity

Description 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].
Related Catalog
References

[1]. Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C10H13FN2O5
Molecular Weight 260.219
Exact Mass 260.080841
PSA 104.55000
LogP -0.72
Index of Refraction 1.593
InChIKey GBBJCSTXCAQSSJ-JXOAFFINSA-N
SMILES Cc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O

 Synonyms

2'-fluoro-5-methyl-2'-deoxy-uridine
MFCD03788702
Thymidine, 2'-fluoro-
2'-Fluorothymidine
2'-deoxy-2'-fluorouridine
2'-Fluor-thymidin
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