EC-11716

Modify Date: 2025-08-23 21:34:00

EC-11716 Structure
EC-11716 structure
 Common Name EC-11716
CAS Number 1235486-15-3 Molecular Weight 457.959
Density N/A Boiling Point N/A
Molecular Formula C23H28ClN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EC-11716


EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).EC/11716 is active against M. abscessus subspecies and clinical isolates, maintains comparable activity against a panel of clinical isolates covering the M. abscessus complex.EC/11716 is effective against M. abscessus biofilms (MIC 0.78 uM), with better bactericidal activity against biofilms than moxifloxacin.EC/11716 is active against M. abscessus in vivo.

 Names

Name EC-11716

 EC-11716 Biological Activity

Description EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).EC/11716 is active against M. abscessus subspecies and clinical isolates, maintains comparable activity against a panel of clinical isolates covering the M. abscessus complex.EC/11716 is effective against M. abscessus biofilms (MIC 0.78 uM), with better bactericidal activity against biofilms than moxifloxacin.EC/11716 is active against M. abscessus in vivo.
References 1. Uday S Ganapathy, et al. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0151421.

 Chemical & Physical Properties

Molecular Formula C23H28ClN5O3
Molecular Weight 457.959
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Chemsrc provides EC-11716(CAS#:1235486-15-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of EC-11716 are included as well.>> amp version: EC-11716

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