rac BHFF
Modify Date: 2024-01-13 22:50:31
rac BHFF structure
|
Common Name | rac BHFF | ||
|---|---|---|---|---|
| CAS Number | 123557-91-5 | Molecular Weight | 330.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H21F3O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of rac BHFFrac-BHFF is a potent and orally active allosteric enhancer of GABAB receptor[1]. |
| Name | 5,7-ditert-butyl-3-hydroxy-3-(trifluoromethyl)-1-benzofuran-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | rac-BHFF is a potent and orally active allosteric enhancer of GABAB receptor[1]. |
|---|---|
| Related Catalog | |
| In Vivo | rac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice[1]. rac-BHFF (3, 10, 30 and 100 mg/kg, p.o.) reverses SIH and high significance was reached for 100 mg kg−1 (P<0.001)[1]. Animal Model: Male NMRI mice (20-25 g)[1]. Dosage: 3, 10, 30 or 100 mg/kg. Administration: P.O.. Result: Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3 mg/kg and above. |
| References |
| Molecular Formula | C17H21F3O3 |
|---|---|
| Molecular Weight | 330.34 |
| Exact Mass | 330.14400 |
| PSA | 46.53000 |
| LogP | 3.95050 |
| Storage condition | -20℃ |
|
~64%
rac BHFF CAS#:123557-91-5 |
| Literature: Malherbe, Parichehr; Masciadri, Raffaello; Norcross, Roger David; Prinssen, Eric Patent: US2007/27204 A1, 2007 ; Location in patent: Page/Page column 8 ; US 20070027204 A1 |
|
~99%
rac BHFF CAS#:123557-91-5 |
| Literature: Dyachenko, V. I.; Galakhov, M. V.; Kolomiets, A. F.; Fokin, A. V. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 4.2 p. 831 - 836 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 4 p. 923 - 928 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| bhff |
| rac bhff |