CGP 36216

Modify Date: 2022-05-20 20:36:49

CGP 36216 structure	Common Name	CGP 36216
	CAS Number	123691-29-2	Molecular Weight	151.14
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅H₁₄NO₂P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CGP 36216

CGP36216 (Compound 9) is a GABAB receptor antagonist. CGP36216 binds to GABAB receptor with a Ki value of 0.3 μM. CGP36216 can be used for research of anxiety and trauma-related disorders[1][2].

Name	(3-Aminopropyl)ethylphosphinic acid hydrochloride (1:1)

Description	CGP36216 (Compound 9) is a GABAB receptor antagonist. CGP36216 binds to GABAB receptor with a Ki value of 0.3 μM. CGP36216 can be used for research of anxiety and trauma-related disorders[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	GABAB receptor[1]
References	[1]. William Howson, et al. Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity. Bioorganic & Medicinal Chemistry Letters. Volume 3, Issue 4, April 1993, Pages 515-518. [2]. Adkins JM, et al. Presynaptic GABAB receptor inhibition sex dependently enhances fear extinction and attenuates fear renewal. Psychopharmacology (Berl). 2021 Aug;238(8):2059-2071.

Molecular Formula	C₅H₁₄NO₂P
Molecular Weight	151.14
Exact Mass	187.05300
PSA	73.13000
LogP	2.12780