Prulifloxacin-d8

Modify Date: 2024-01-14 15:34:42

Prulifloxacin-d8 structure	Common Name	Prulifloxacin-d8
	CAS Number	1246819-37-3	Molecular Weight	469.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₂D₈FN₃O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Prulifloxacin-d8

Prulifloxacin-d8 (NM441-d8) is the deuterium labeled Prulifloxacin. Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a prodrug of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis[1][2].

Name	Prulifloxacin-d8

Description	Prulifloxacin-d8 (NM441-d8) is the deuterium labeled Prulifloxacin. Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a prodrug of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. 4/ [2]. M Ozaki, et al. In vivo evaluation of NM441, a new thiazeto-quinoline derivative. Antimicrob Agents Chemother. 1991 Dec;35(12):2496-9. [3]. Guillem Prats, et al. Prulifloxacin: a new antibacterial fluoroquinolone. Expert Rev Anti Infect Ther. 2006 Feb;4(1):27-41.

Molecular Formula	C₂₁H₁₂D₈FN₃O₆S
Molecular Weight	469.51

Prulifloxacin-d8

Use of Prulifloxacin-d8

Names

Prulifloxacin-d8 Biological Activity

Chemical & Physical Properties