diethyl 8-bromooctylphosphonate

Modify Date: 2024-01-10 14:51:11

diethyl 8-bromooctylphosphonate structure	Common Name	diethyl 8-bromooctylphosphonate
	CAS Number	124939-70-4	Molecular Weight	329.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₂₆BrO₃P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of diethyl 8-bromooctylphosphonate

Diethyl 8-bromooctylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Diethyl 8-bromooctylphosphonate
Synonym	More Synonyms

Description	Diethyl 8-bromooctylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₂H₂₆BrO₃P
Molecular Weight	329.21

MFCD24539460

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