diethyl 8-bromooctylphosphonate

Modify Date: 2024-01-10 14:51:11

diethyl 8-bromooctylphosphonate Structure
diethyl 8-bromooctylphosphonate structure
Common Name diethyl 8-bromooctylphosphonate
CAS Number 124939-70-4 Molecular Weight 329.21
Density N/A Boiling Point N/A
Molecular Formula C12H26BrO3P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of diethyl 8-bromooctylphosphonate


Diethyl 8-bromooctylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diethyl 8-bromooctylphosphonate
Synonym More Synonyms

 diethyl 8-bromooctylphosphonate Biological Activity

Description Diethyl 8-bromooctylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H26BrO3P
Molecular Weight 329.21

 Synonyms

MFCD24539460
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