3’-Deoxy-3’-fluoro-5-methyluridine

Modify Date: 2024-01-28 08:07:07

3’-Deoxy-3’-fluoro-5-methyluridine Structure
3’-Deoxy-3’-fluoro-5-methyluridine structure
Common Name 3’-Deoxy-3’-fluoro-5-methyluridine
CAS Number 125217-37-0 Molecular Weight 260.22
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Deoxy-3’-fluoro-5-methyluridine


3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Deoxy-3'-fluoro-5-methyluridine
Synonym More Synonyms

 3’-Deoxy-3’-fluoro-5-methyluridine Biological Activity

Description 3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C10H13FN2O5
Molecular Weight 260.22
Exact Mass 260.080841
LogP -0.59
Index of Refraction 1.593

 Synonyms

3'-Deoxy-3'-fluoro-5-methyluridine
MFCD27921028
1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)thymine
Uridine, 3'-deoxy-3'-fluoro-5-methyl-