N-methyl-N-(t-Boc)-PEG4-acid

Modify Date: 2025-08-27 17:34:39

N-methyl-N-(t-Boc)-PEG4-acid structure	Common Name	N-methyl-N-(t-Boc)-PEG4-acid
	CAS Number	1260431-01-3	Molecular Weight	379.446
	Density	1.1±0.1 g/cm3	Boiling Point	488.2±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₃₃NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	249.1±28.7 °C

Use of N-methyl-N-(t-Boc)-PEG4-acid

N-Methyl-N-(t-Boc)-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-methyl-N-(t-Boc)-PEG4-acid
Synonym	More Synonyms

Description	N-Methyl-N-(t-Boc)-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.1±0.1 g/cm3
Boiling Point	488.2±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₃₃NO₈
Molecular Weight	379.446
Flash Point	249.1±28.7 °C
Exact Mass	379.220612
LogP	0.35
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.470
InChIKey	SZYFMMNWNDIBGM-UHFFFAOYSA-N
SMILES	CN(CCOCCOCCOCCOCCC(=O)O)C(=O)OC(C)(C)C

2,2,5-Trimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid

MFCD28950776

3,8,11,14,17-Pentaoxa-5-azaeicosan-20-oic acid, 2,2,5-trimethyl-4-oxo-

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