8-Allyloxyguanosine

Modify Date: 2024-01-11 14:41:02

8-Allyloxyguanosine Structure
8-Allyloxyguanosine structure
Common Name 8-Allyloxyguanosine
CAS Number 126138-81-6 Molecular Weight 339.30
Density 1.892 g/cm3 Boiling Point N/A
Molecular Formula C13H17N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-Allyloxyguanosine


8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 8-(Allyloxy)guanosine
Synonym More Synonyms

 8-Allyloxyguanosine Biological Activity

Description 8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.892 g/cm3
Molecular Formula C13H17N5O6
Molecular Weight 339.30
Exact Mass 339.11800
PSA 168.74000
Index of Refraction 1.789

 Synthetic Route

~63%

8-Allyloxyguanosine Structure

8-Allyloxyguanosine

CAS#:126138-81-6

Literature: Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 551 - 562

~19%

8-Allyloxyguanosine Structure

8-Allyloxyguanosine

CAS#:126138-81-6

Literature: US5011828 A1, ;

~68%

8-Allyloxyguanosine Structure

8-Allyloxyguanosine

CAS#:126138-81-6

Literature: Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3561 - 3578

 Synonyms

8-(2-Propenyl)oxyguanosine
8-(allyloxy)-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one