Cyclobenzaprine-13C,d3 hydrochloride

Modify Date: 2024-01-29 10:18:35

Cyclobenzaprine-13C,d3 hydrochloride Structure
Cyclobenzaprine-13C,d3 hydrochloride structure
Common Name Cyclobenzaprine-13C,d3 hydrochloride
CAS Number 1261394-10-8 Molecular Weight 315.86
Density N/A Boiling Point N/A
Molecular Formula C1913CH19D3ClN Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclobenzaprine-13C,d3 hydrochloride


Cyclobenzaprine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled.

 Names

Name Cyclobenzaprine-13C,d3 hydrochloride

 Cyclobenzaprine-13C,d3 hydrochloride Biological Activity

Description Cyclobenzaprine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[60].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

[2]. Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35.

[3]. Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9.

 Chemical & Physical Properties

Molecular Formula C1913CH19D3ClN
Molecular Weight 315.86