ASP6432

Modify Date: 2025-08-26 08:18:13

ASP6432 Structure
ASP6432 structure
Common Name ASP6432
CAS Number 1282549-08-9 Molecular Weight 598.78
Density N/A Boiling Point N/A
Molecular Formula C26H31KN4O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ASP6432


ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively[1].

 Names

Name ASP6432

 ASP6432 Biological Activity

Description ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively[1].
Related Catalog
Target

IC50: 11 nM (human LPA1), 30 nM (rat LPA1)[1]

In Vitro ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells[1].
References

[1]. Sakamoto K, et al. Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation. J Pharmacol Exp Ther. 2018 Aug;366(2):390-396.

 Chemical & Physical Properties

Molecular Formula C26H31KN4O6S2
Molecular Weight 598.78
InChIKey WKYBXXHNGOTYDD-UHFFFAOYSA-M
SMILES CCNS(=O)(=O)[N-]C(=O)c1csc(CN(CCCc2ccccc2)C(=O)c2cc(OC)c(C)c(OC)c2)n1.[K+]
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