3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine

Modify Date: 2024-02-04 20:26:34

3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine Structure
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine structure
Common Name 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine
CAS Number 128495-99-8 Molecular Weight 453.42
Density 1.4±0.1 g/cm3 Boiling Point 617.3±65.0 °C at 760 mmHg
Molecular Formula C23H20FN3O6 Melting Point N/A
MSDS N/A Flash Point 327.1±34.3 °C

 Use of 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine


3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 4-Amino-1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone
Synonym More Synonyms

  Biological Activity

Description 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 617.3±65.0 °C at 760 mmHg
Molecular Formula C23H20FN3O6
Molecular Weight 453.42
Flash Point 327.1±34.3 °C
Exact Mass 453.133606
LogP 3.78
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.643

 Synonyms

2(1H)-Pyrimidinone, 4-amino-1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
MFCD25542521
4-Amino-1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone