MC2050 HCl

Modify Date: 2024-02-07 16:14:17

MC2050 HCl Structure
MC2050 HCl structure
Common Name MC2050 HCl
CAS Number 1301757-19-6 Molecular Weight 440.387
Density N/A Boiling Point N/A
Molecular Formula C19H23Cl2N5Os Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC2050 HCl


MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.

 Names

Name MC2050 HCl

 MC2050 HCl Biological Activity

Description MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.

 Chemical & Physical Properties

Molecular Formula C19H23Cl2N5Os
Molecular Weight 440.387
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