VU0360172
Modify Date: 2024-01-02 17:58:08
VU0360172 structure
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Common Name | VU0360172 | ||
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| CAS Number | 1310012-12-4 | Molecular Weight | 294.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H15FN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VU0360172VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[1]. |
| Name | VU0360172 |
|---|
| Description | VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[1]. |
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| Related Catalog | |
| Target |
EC50: 16 nM (mGlu5 receptor)[1] Ki: 195 nM (mGlu5 receptor)[1] |
| References |
| Molecular Formula | C18H15FN2O |
|---|---|
| Molecular Weight | 294.32 |