BACE1-IN-1
BACE1-IN-1 structure
|
Common Name | BACE1-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1310347-50-2 | Molecular Weight | 389.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H14F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BACE1-IN-1BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | BACE1-IN-1 |
|---|
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. |
|---|---|
| Related Catalog | |
| Target |
IC50: 32 nM (human BACE1), 47 nM (human BACE2)[1] |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C18H14F3N5O2 |
|---|---|
| Molecular Weight | 389.33 |
| InChIKey | DVMUZHLUMHPCGZ-QGZVFWFLSA-N |
| SMILES | CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)N=C(N)OCC1(F)F |
| Storage condition | 2-8℃ |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of BACE1-IN-1? |
| A: InChIKey of BACE1-IN-1 is DVMUZHLUMHPCGZ-QGZVFWFLSA-N. |
| Q: What are the storage conditions for BACE1-IN-1? |
| A: Storage conditions for BACE1-IN-1: 2-8℃. |
| Q: What is the English name of BACE1-IN-1? |
| A: The English name of BACE1-IN-1 is BACE1-IN-1. |
| Q: What is the Chinese name of 1310347-50-2? |
| A: Chinese name of 1310347-50-2 is BACE1-IN-1. |
| Q: What are the uses of BACE1-IN-1? |
| A: Main uses of BACE1-IN-1: BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. |
| Q: What is the molecular formula of BACE1-IN-1? |
| A: Molecular formula of BACE1-IN-1 is C18H14F3N5O2. |
| Q: What is the SMILES notation of BACE1-IN-1? |
| A: SMILES notation of BACE1-IN-1 is CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)N=C(N)OCC1(F)F. |
| Q: What is the molecular weight of BACE1-IN-1? |
| A: Molecular weight of BACE1-IN-1 is 389.33. |
| Q: What is the CAS number of BACE1-IN-1? |
| A: CAS number of BACE1-IN-1 is 1310347-50-2. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |