Radalbuvir
Modify Date: 2024-01-12 07:40:08
Radalbuvir structure
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Common Name | Radalbuvir | ||
|---|---|---|---|---|
| CAS Number | 1314795-11-3 | Molecular Weight | 543.715 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 721.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C30H41NO6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 389.9±32.9 °C | |
Use of RadalbuvirRadalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM)[1]. |
| Name | radalbuvir |
|---|---|
| Synonym | More Synonyms |
| Description | Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM)[1]. |
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| Related Catalog | |
| In Vitro | Radalbuvir (GS-9669) shows high in vitro metabolic stability, long residence time in rats, and maintained high activity against the NS5B M423T mutation (GT1b M423T EC50 = 14 nM)[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 721.2±60.0 °C at 760 mmHg |
| Molecular Formula | C30H41NO6S |
| Molecular Weight | 543.715 |
| Flash Point | 389.9±32.9 °C |
| Exact Mass | 543.265442 |
| LogP | 4.17 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.599 |
| 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxy-4-{[(3S)-tetrahydro-3-furanyloxy]methyl}cyclohexyl){[(1R)-4-methyl-3-cyclohexen-1-yl]carbonyl}amino]-2-thiophenecarboxylic acid |
| radalbuvir |
| UNII-273K4V0SPC |
| 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[[cis-4-hydroxy-4-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]cyclohexyl][[(1R)-4-methyl-3-cyclohexen-1-yl]carbonyl]amino]- |