Rifamycin,3-[(1-piperazinylimino)methyl]-

Modify Date: 2025-08-27 09:46:26

Rifamycin,3-[(1-piperazinylimino)methyl]- Structure
Rifamycin,3-[(1-piperazinylimino)methyl]- structure
Common Name Rifamycin,3-[(1-piperazinylimino)methyl]-
CAS Number 13292-45-0 Molecular Weight 808.91400
Density 1.35g/cm3 Boiling Point N/A
Molecular Formula C42H56N4O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name N-Demethyl Rifampin
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.35g/cm3
Molecular Formula C42H56N4O12
Molecular Weight 808.91400
Exact Mass 808.38900
PSA 228.94000
LogP 4.39790
Index of Refraction 1.631

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1923000
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl -8-(N-1-piperazinylfo rmimidoyl)-, 21- acetate
CAS REGISTRY NUMBER :
13292-45-0
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C42-H56-N4-O12
MOLECULAR WEIGHT :
809.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
695 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
100 mg/L
REFERENCE :
BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 60,96,1974

 Synonyms

4-N-Demethylrifampicin
rifaldehyde piperazin-1-ylhydrazone
Rifampicin AF/AP
3-(piperazin-1-ylimino-methyl)-rifamycin
N-Demethylrifampin
AF/AP
N-Demethylrifampicin
Rifampicin AF/A
3-(piperidinyliminomethyl)rifamycin SV
Demethylrifampicin
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