Pitstop 1
Modify Date: 2025-08-27 18:56:30
Pitstop 1 structure
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Common Name | Pitstop 1 | ||
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| CAS Number | 1332879-51-2 | Molecular Weight | 404.372 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H13N2NaO5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Pitstop 1A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ. |
| Name | Sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate |
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| Synonym | More Synonyms |
| Description | A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ. |
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| References | References 1. von Kleist L, et al. Cell. 2011 Aug 5;146(3):471-84. 2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138. View Related Products by Target Clathrin |
| Molecular Formula | C19H13N2NaO5S |
|---|---|
| Molecular Weight | 404.372 |
| Exact Mass | 404.044281 |
| InChIKey | MKPPGLKJTZAXNE-UHFFFAOYSA-M |
| SMILES | Nc1ccc(CN2C(=O)c3cccc4cc(S(=O)(=O)[O-])cc(c34)C2=O)cc1.[Na+] |
| Sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate |
| 1H-Benz[de]isoquinoline-5-sulfonic acid, 2-[(4-aminophenyl)methyl]-2,3-dihydro-1,3-dioxo-, sodium salt (1:1) |