5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Modify Date: 2024-01-31 20:08:38

5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol Structure
5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol structure
 Common Name 5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
CAS Number 13389-10-1 Molecular Weight 280.28
Density 1.85g/cm3 Boiling Point 634.5ºC at 760 mmHg
Molecular Formula C11H16N6O3 Melting Point N/A
MSDS N/A Flash Point 337.5ºC

 Use of 5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol


2'-Deoxy-8-methylamino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-[6-amino-8-(methylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol
Synonym More Synonyms

  Biological Activity

Description 2'-Deoxy-8-methylamino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.85g/cm3
Boiling Point 634.5ºC at 760 mmHg
Molecular Formula C11H16N6O3
Molecular Weight 280.28
Flash Point 337.5ºC
Exact Mass 280.12800
PSA 131.34000
Vapour Pressure 5.72E-17mmHg at 25°C
Index of Refraction 1.836

 Synonyms

9-(2-deoxypentofuranosyl)-n8-methyl-9h-purine-6,8-diamine
8-methylamino-2'-deoxy-adenosine
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Chemsrc provides CAS#:13389-10-1 MSDS, density, melting point, boiling point, structure, etc. Its name is 5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol>> amp version: 5-(6-amino-8-methylamino-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

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