IRE1α kinase-IN-9

Modify Date: 2025-11-27 20:51:19

IRE1α kinase-IN-9 Structure
IRE1α kinase-IN-9 structure
Common Name IRE1α kinase-IN-9
CAS Number 1338933-30-4 Molecular Weight 436.46
Density N/A Boiling Point N/A
Molecular Formula C24H24N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IRE1α kinase-IN-9


IRE1α kinase-IN-9 (compound 2) is a potent IRE-1α inhibitor,exhibits an average IC50 value of <0.1 μM. IRE1α kinase-IN-9 can be used for research in diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD)[1].

 Names

Name IRE1α kinase-IN-9

 IRE1α kinase-IN-9 Biological Activity

Description IRE1α kinase-IN-9 (compound 2) is a potent IRE-1α inhibitor,exhibits an average IC50 value of <0.1 μM. IRE1α kinase-IN-9 can be used for research in diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD)[1].
Related Catalog
Target

IC50: <0.1 μM (IRE1α)[1]

References

[1]. Zeng Q, et al. Benzoheterocyclecarboxaldehyde derivatives as IRE-1α inhibitors and their preparation and use for the treatment of diseases. World Intellectual Property Organization, WO2011127070 A2. 2011-10-13.

 Chemical & Physical Properties

Molecular Formula C24H24N2O6
Molecular Weight 436.46
InChIKey NQUKAQJMGQBCMS-UHFFFAOYSA-N
SMILES Cc1c(-c2ccc(C(=O)NCCN3CCOCC3)cc2)c(=O)oc2c(C=O)c(O)ccc12
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