N-trifluoroacetyl (TFA)
Modify Date: 2025-08-24 20:28:29
N-trifluoroacetyl (TFA) structure
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Common Name | N-trifluoroacetyl (TFA) | ||
|---|---|---|---|---|
| CAS Number | 133975-85-6 | Molecular Weight | 413.41500 | |
| Density | N/A | Boiling Point | 433.696ºC at 760 mmHg | |
| Molecular Formula | C17H31F3N3O3P | Melting Point | N/A | |
| MSDS | USA | Flash Point | 216.092ºC | |
Use of N-trifluoroacetyl (TFA)N-trifluoroacetyl (TFA) protected aminolink C6 phosphoramidite for the synthesis of 5'-amino-modified oligonucleotides. TFA protection is smoothly removed during ammonia deprotection, and does not require any additional steps. If necessary, the resulting oligonucleotides can be purified by ion exchange chromatography, or gel electrophoresis. |
| Name | 5'-amino-modifier-c 6-tfa cep |
|---|---|
| Synonym | More Synonyms |
| Boiling Point | 433.696ºC at 760 mmHg |
|---|---|
| Molecular Formula | C17H31F3N3O3P |
| Molecular Weight | 413.41500 |
| Flash Point | 216.092ºC |
| Exact Mass | 413.20600 |
| PSA | 88.18000 |
| LogP | 4.90878 |
| Vapour Pressure | 0mmHg at 25°C |
| InChIKey | SMMKTKILBQHSFL-UHFFFAOYSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OCCCCCCNC(=O)C(F)(F)F |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
|---|
| C6 TFA LINKER AMIDITE |
| trifluoroacetyl cyanoethyl phosphoramidite amino-linker |