2-Chloro-N6-methyladenosine

Modify Date: 2024-04-02 17:38:03

2-Chloro-N6-methyladenosine structure	Common Name	2-Chloro-N6-methyladenosine
	CAS Number	13406-50-3	Molecular Weight	315.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₄ClN₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-Chloro-N6-methyladenosine

2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,4S,5R)-2-[2-chloro-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Synonym	More Synonyms

Description	2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₁H₁₄ClN₅O₄
Molecular Weight	315.71
Exact Mass	315.07300
PSA	125.55000

2-chloro-N6-methyladenosine

(4S,2R,3R,5R)-2-[2-chloro-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Adenosine,2-chloro-N-methyl

2-Chloro-N6-methyladenosin

2-Chloro-N6-methyladenosine

Use of 2-Chloro-N6-methyladenosine

Names

2-Chloro-N6-methyladenosine Biological Activity

Chemical & Physical Properties

Synonyms