Cbz-NH-PEG2-C2-acid

Modify Date: 2024-01-06 20:47:33

Cbz-NH-PEG2-C2-acid Structure
Cbz-NH-PEG2-C2-acid structure
Common Name Cbz-NH-PEG2-C2-acid
CAS Number 1347750-76-8 Molecular Weight 311.33
Density N/A Boiling Point N/A
Molecular Formula C15H21NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-NH-PEG2-C2-acid


Cbz-NH-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Cbz-N-amido-PEG2-acid
Synonym More Synonyms

 Cbz-NH-PEG2-C2-acid Biological Activity

Description Cbz-NH-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H21NO6
Molecular Weight 311.33
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synonyms

CBZ-N-AMIDO-PEG2-COOH
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