Dnp-PYAYWMR (trifluoroacetate salt)

Modify Date: 2024-01-09 10:24:06

Dnp-PYAYWMR (trifluoroacetate salt) Structure
Dnp-PYAYWMR (trifluoroacetate salt) structure
Common Name Dnp-PYAYWMR (trifluoroacetate salt)
CAS Number 135662-06-5 Molecular Weight 1266.261
Density N/A Boiling Point N/A
Molecular Formula C56H66F3N13O16S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dnp-PYAYWMR (trifluoroacetate salt)


Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].

 Names

Name Dnp-PYAYWMR (trifluoroacetate salt)
Synonym More Synonyms

 Dnp-PYAYWMR (trifluoroacetate salt) Biological Activity

Description Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].
Related Catalog
Target

MMP3[1]

References

[1]. Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11(20):6009-6018.  

 Chemical & Physical Properties

Molecular Formula C56H66F3N13O16S
Molecular Weight 1266.261
Exact Mass 1265.442383

 Synonyms

L-Arginine, 1-(2,4-dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)
Dnp-PYAYWMR (trifluoroacetate salt)
1-(2,4-Dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-L-arginine trifluoroacetate (1:1)