Big endothelin-1 (rat 1-39)
Big endothelin-1 (rat 1-39) structure
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Common Name | Big endothelin-1 (rat 1-39) | ||
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| CAS Number | 135842-15-8 | Molecular Weight | 4389 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C192H292N50O58S5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Big endothelin-1 (rat 1-39)Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice[1]. |
| Name | BIG ENDOTHELIN-1 (1-39) (RAT) |
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| Synonym | More Synonyms |
| Description | Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C192H292N50O58S5 |
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| Molecular Weight | 4389 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling.
Circulation 96(11) , 3963-73, (1997) Left ventricular dilatation after myocardial infarction is associated with impaired ventricular function and heart failure and has important implications for survival. The purpose of this study was to... |
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Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro.
Proc. Natl. Acad. Sci. U. S. A. 88(3) , 703-7, (1991) In porcine aortic endothelial cells, the 21-amino acid peptide endothelin-1 (ET-1) is formed from a 39-amino acid intermediate called "big endothelin-1" (big ET-1) by a putative ET-converting enzyme (... |
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Phosphoramidon blocks big-endothelin-1 but not endothelin-1 enhancement of vascular permeability in the rat.
Br. J. Pharmacol. 107(4) , 996-1000, (1992) 1. Changes in vascular permeability following intravenous injections of human big-endothelin-1 (big-ET-1) and endothelin-1 (ET-1) were measured by extravasation of Evans blue dye (EB, 20 mg kg-1) in s... |
| CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER |