N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide

Modify Date: 2025-07-24 16:17:35

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide Structure
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide structure
Common Name N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS Number 1383373-65-6 Molecular Weight 399.87
Density N/A Boiling Point N/A
Molecular Formula C24H18ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide


N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

 Names

Name N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide

  Biological Activity

Description N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
References 1. REMYND; KATHOLIEKE UNIVERSITEIT LEUVEN - WO2012/80220, 2012, A1

 Chemical & Physical Properties

Molecular Formula C24H18ClN3O
Molecular Weight 399.87
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