7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl-

Modify Date: 2024-01-09 18:11:30

7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl- structure	Common Name	7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl-
	CAS Number	13877-76-4	Molecular Weight	268.22600
	Density	2.18g/cm3	Boiling Point	683.2ºC at 760mmHg
	Molecular Formula	C₁₀H₁₂N₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	367ºC

Name	formycin B
Synonym	More Synonyms

Density	2.18g/cm3
Boiling Point	683.2ºC at 760mmHg
Molecular Formula	C₁₀H₁₂N₄O₅
Molecular Weight	268.22600
Flash Point	367ºC
Exact Mass	268.08100
PSA	144.35000
Vapour Pressure	1.34E-19mmHg at 25°C
Index of Refraction	1.921

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR0800000

CHEMICAL NAME :: 7H-Pyrazolo(4,3-d)pyrimidin-7-one, 1,4-dihydro-3-beta-D-ribofuranosyl-

CAS REGISTRY NUMBER :: 13877-76-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H12-N4-O5

MOLECULAR WEIGHT :: 268.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg/10D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 30,2651,1981

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Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

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Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

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Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

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N/A

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7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl- Structure

7H-Pyrazolo[4,3...

CAS#:13877-76-4

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

N/A structure

N/A

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CAS#:13877-76-4

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

Precursor 3
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DownStream 3
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FORMYCIN B

LAURUSIN

D-Ribitol, 1,4-anhydro-1-C-(6,7-dihydro-7-oxo-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-, (S)-

OHYAMYCIN