5-HT2A receptor agonist-3

Modify Date: 2024-09-18 11:24:17

5-HT2A receptor agonist-3 Structure
5-HT2A receptor agonist-3 structure
Common Name 5-HT2A receptor agonist-3
CAS Number 1391499-52-7 Molecular Weight 420.34
Density N/A Boiling Point N/A
Molecular Formula C21H26BrNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-HT2A receptor agonist-3


5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].

 Names

Name 5-HT2A receptor agonist-3

 5-HT2A receptor agonist-3 Biological Activity

Description 5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].
Related Catalog
Target

2.5 nM (human 5-HT2A)

References

[1]. Juncosa JI Jr, et al. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. ACS Chem Neurosci. 2013;4(1):96-109.  

 Chemical & Physical Properties

Molecular Formula C21H26BrNO3
Molecular Weight 420.34