VU0455691

Modify Date: 2025-09-05 09:55:51

VU0455691 structure	Common Name	VU0455691
	CAS Number	1392443-41-2	Molecular Weight	463.55200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₅N₅O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VU0455691

VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1)[1].

Name	[Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone

Description	VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR
References	[1]. Melancon BJ, et al. Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Bioorg Med Chem Lett. 2012;22(15):5035-5040.

Molecular Formula	C₂₄H₂₅N₅O₃S
Molecular Weight	463.55200
Exact Mass	463.16800
PSA	95.09000
LogP	2.86670

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VU0455691
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: VU0455691
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: [Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-Methanone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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