1-Phenazinol,6-methoxy-, 5,10-dioxide

Modify Date: 2024-01-10 15:25:22

1-Phenazinol,6-methoxy-, 5,10-dioxide Structure
1-Phenazinol,6-methoxy-, 5,10-dioxide structure
 Common Name 1-Phenazinol,6-methoxy-, 5,10-dioxide
CAS Number 13925-12-7 Molecular Weight 258.23000
Density 1.53g/cm3 Boiling Point 538.8ºC at 760mmHg
Molecular Formula C13H10N2O4 Melting Point N/A
MSDS N/A Flash Point 279.7ºC

 Use of 1-Phenazinol,6-methoxy-, 5,10-dioxide


Myxin is a di-N-oxide phenazine produced by Lysobacter antibioticus OH13. Myxin is toxic to many microorganisms and tumor cells[1].

 Names

Name 5-hydroxy-6-methoxy-10-oxidophenazin-10-ium-1-one
Synonym More Synonyms

 1-Phenazinol,6-methoxy-, 5,10-dioxide Biological Activity

Description Myxin is a di-N-oxide phenazine produced by Lysobacter antibioticus OH13. Myxin is toxic to many microorganisms and tumor cells[1].
Related Catalog
References

[1]. Liu J, et al. Monooxygenase LaPhzX is Involved in Self-Resistance Mechanisms during the Biosynthesis of N-Oxide Phenazine Myxin. J Agric Food Chem. 2021;69(45):13524-13532.

 Chemical & Physical Properties

Density 1.53g/cm3
Boiling Point 538.8ºC at 760mmHg
Molecular Formula C13H10N2O4
Molecular Weight 258.23000
Flash Point 279.7ºC
Exact Mass 258.06400
PSA 80.38000
LogP 2.56420
Vapour Pressure 1.93E-12mmHg at 25°C
Index of Refraction 1.73

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SG1660000
CHEMICAL NAME :
1-Phenazinol, 6-methoxy-, 5,10-dioxide
CAS REGISTRY NUMBER :
13925-12-7
BEILSTEIN REFERENCE NO. :
0622031
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C13-H10-N2-O4
MOLECULAR WEIGHT :
258.25
WISWESSER LINE NOTATION :
T C666 BN INJ BO DQ IO KO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
133 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Protozoa - Euglena gracilis
DOSE/DURATION :
10 mg/L
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 27,586,1971

 Safety Information

HS Code 2933990090

 Synthetic Route

6-Methoxyphenazin-1-ol structure

6-Methoxyphenaz...

CAS#:13129-58-3

~7%

6-methoxy-10-oxido-5H-phenazin-10-ium-1-one structure

6-methoxy-10-ox...

CAS#:13129-57-2

1-Phenazinol,6-methoxy-, 5,10-dioxide Structure

1-Phenazinol,6-...

CAS#:13925-12-7

Literature: Chowdhury, Goutam; Sarkar, Ujjal; Pullen, Susan; Wilson, William R.; Rajapakse, Anuruddha; Fuchs-Knotts, Tarra; Gates, Kent S. Chemical Research in Toxicology, 2012 , vol. 25, # 1 p. 197 - 206
nitroanisole structure

nitroanisole

CAS#:91-23-6

~%

1-Phenazinol,6-methoxy-, 5,10-dioxide Structure

1-Phenazinol,6-...

CAS#:13925-12-7

Literature: Chowdhury, Goutam; Sarkar, Ujjal; Pullen, Susan; Wilson, William R.; Rajapakse, Anuruddha; Fuchs-Knotts, Tarra; Gates, Kent S. Chemical Research in Toxicology, 2012 , vol. 25, # 1 p. 197 - 206
1,6-Dimethoxyphenazine structure

1,6-Dimethoxyph...

CAS#:13398-79-3

~%

1-Phenazinol,6-methoxy-, 5,10-dioxide Structure

1-Phenazinol,6-...

CAS#:13925-12-7

Literature: Chowdhury, Goutam; Sarkar, Ujjal; Pullen, Susan; Wilson, William R.; Rajapakse, Anuruddha; Fuchs-Knotts, Tarra; Gates, Kent S. Chemical Research in Toxicology, 2012 , vol. 25, # 1 p. 197 - 206
2-Anisidine structure

2-Anisidine

CAS#:90-04-0

~%

1-Phenazinol,6-methoxy-, 5,10-dioxide Structure

1-Phenazinol,6-...

CAS#:13925-12-7

Literature: Chowdhury, Goutam; Sarkar, Ujjal; Pullen, Susan; Wilson, William R.; Rajapakse, Anuruddha; Fuchs-Knotts, Tarra; Gates, Kent S. Chemical Research in Toxicology, 2012 , vol. 25, # 1 p. 197 - 206

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Myxin
6-Methoxy-1-phenazinol 5,10-dioxide
1-Hydroxy-6-methoxyphenazine 5,10-dioxide
1-hydroxy-6-methoxyphenazine N5,N10-dioxide
3C Antibiotic
1-Phenazinol,6-methoxy-,5,10-dioxide
6-methoxy-5,10-dioxy-phenazin-1-ol
1-Methoxy-6-hydroxyphenazin-5,10-dioxid
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Chemsrc provides 1-Phenazinol,6-methoxy-, 5,10-dioxide(CAS#:13925-12-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 1-Phenazinol,6-methoxy-, 5,10-dioxide are included as well.>> amp version: 1-Phenazinol,6-methoxy-, 5,10-dioxide

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