TRV0109101

Modify Date: 2024-09-13 20:23:22

TRV0109101 Structure
TRV0109101 structure
Common Name TRV0109101
CAS Number 1401027-29-9 Molecular Weight 356.525
Density 1.2±0.1 g/cm3 Boiling Point 504.1±40.0 °C at 760 mmHg
Molecular Formula C21H28N2OS Melting Point N/A
MSDS N/A Flash Point 258.7±27.3 °C

 Use of TRV0109101


A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

 Names

Name 2-[(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]dec-9-yl]-N-(2-thienylmethyl)ethanamine
Synonym More Synonyms

 TRV0109101 Biological Activity

Description A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.
References References 1. Koblish M, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):254-262. View Related Products by Target Opioid Receptor

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 504.1±40.0 °C at 760 mmHg
Molecular Formula C21H28N2OS
Molecular Weight 356.525
Flash Point 258.7±27.3 °C
Exact Mass 356.192230
LogP 3.53
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.597

 Synonyms

2-[(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]dec-9-yl]-N-(2-thienylmethyl)ethanamine
6-Oxaspiro[4.5]decane-9-ethanamine, 9-(2-pyridinyl)-N-(2-thienylmethyl)-, (9R)-
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