Ald-Ph-amido-PEG3-C2-NH2

Modify Date: 2024-01-04 09:15:09

Ald-Ph-amido-PEG3-C2-NH2 Structure
Ald-Ph-amido-PEG3-C2-NH2 structure
Common Name Ald-Ph-amido-PEG3-C2-NH2
CAS Number 1404111-56-3 Molecular Weight 324.372
Density 1.2±0.1 g/cm3 Boiling Point 542.8±50.0 °C at 760 mmHg
Molecular Formula C16H24N2O5 Melting Point N/A
MSDS N/A Flash Point 282.1±30.1 °C

 Use of Ald-Ph-amido-PEG3-C2-NH2


Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ald--Ph-PEG3-amine
Synonym More Synonyms

 Ald-Ph-amido-PEG3-C2-NH2 Biological Activity

Description Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 542.8±50.0 °C at 760 mmHg
Molecular Formula C16H24N2O5
Molecular Weight 324.372
Flash Point 282.1±30.1 °C
Exact Mass 324.168518
LogP -0.57
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.540

 Safety Information

Hazard Codes Xi

 Synonyms

ALD-PH-NH-PEG3-NH2