(2,3-Difluoro-6-nitrophenyl)acetic acid

Modify Date: 2026-07-17 09:42:46

(2,3-Difluoro-6-nitrophenyl)acetic acid Structure
(2,3-Difluoro-6-nitrophenyl)acetic acid structure
Common Name (2,3-Difluoro-6-nitrophenyl)acetic acid
CAS Number 141428-47-9 Molecular Weight 217.126
Density 1.6±0.1 g/cm3 Boiling Point 345.1±37.0 °C at 760 mmHg
Molecular Formula C8H5F2NO4 Melting Point N/A
MSDS N/A Flash Point 162.5±26.5 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-(2,3-Difluoro-6-nitrophenyl)acetic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.6±0.1 g/cm3
Boiling Point 345.1±37.0 °C at 760 mmHg
Molecular Formula C8H5F2NO4
Molecular Weight 217.126
Flash Point 162.5±26.5 °C
Exact Mass 217.018661
PSA 83.12000
LogP 0.95
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.553
InChIKey KZNVCGPCWKYPKD-UHFFFAOYSA-N
SMILES O=C(O)Cc1c([N+](=O)[O-])ccc(F)c1F

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

2,3-Difluoro-6-nitrophenylacetic Acid
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:2,3-Difluoro-6-nitrophenylacetic Acid
5.3

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS
Skin corrosion/irritationCategory 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDSNot classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal wordWarning
Hazard statementsCauses skin irritation
Causes serious eye irritation
Precautionary statements:
Wash hands thoroughly after handling.
[Prevention]
Wear protective gloves/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
[Response]
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:2,3-Difluoro-6-nitrophenylacetic Acid
Percent:>98.0%(GC)(T)
CAS Number:141428-47-9
Chemical Formula:C8H5F2NO4

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
2,3-Difluoro-6-nitrophenylacetic Acid

Section4. FIRST AID MEASURES
Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth.
A rescuer should wear personal protective equipment, such as rubber gloves and air-
Protection of first-aiders:
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Suitable extinguishingDry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical:generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls:Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Safety glasses. A face-shield, if the situation requires.
Eye protection:
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Crystal- Powder
Form:
Colour:Slightly pale yellow - Yellow
No data available
Odour:
2,3-Difluoro-6-nitrophenylacetic Acid

Section9. PHYSICAL AND CHEMICAL PROPERTIES
pH: No data available
Melting point/freezing point:156°C
Boiling point/range:No data available
Flash point:No data available
Flammability or explosive
limits:
Lower:No data available
Upper:No data available
Relative density:No data available
Solubility(ies):
[Water]No data available
[Other solvents]
Slightly soluble:Methanol

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen fluoride
products:

Section11. TOXICOLOGICAL INFORMATION
Acute Toxicity:No data available
Skin corrosion/irritation: No data available
Serious eyeNo data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
Reproductive toxicity:No data available

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
No data available
Algae:
Persistence / degradability: No data available
No data available
Bioaccumulative
potential(BCF):
Mobility in soil
Log Pow:No data available
Soil adsorption (Koc):No data available
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
UN-No:Not listed
2,3-Difluoro-6-nitrophenylacetic Acid

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2916399090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~%

(2,3-Difluoro-6-nitrophenyl)acetic acid Structure

(2,3-Difluoro-6...

CAS#:141428-47-9

Learn More
Literature: US2006/30609 A1, ; Page/Page column 17 ;

~%

(2,3-Difluoro-6-nitrophenyl)acetic acid Structure

(2,3-Difluoro-6...

CAS#:141428-47-9

Learn More
Literature: WO2007/36715 A2, ; Page/Page column 48 ; WO 2007/036715 A2

~59%

(2,3-Difluoro-6-nitrophenyl)acetic acid Structure

(2,3-Difluoro-6...

CAS#:141428-47-9

Learn More
Literature: Lee, Lily; Kreutter, Kevin D.; Pan, Wenxi; Crysler, Carl; Spurlino, John; Player, Mark R.; Tomczuk, Bruce; Lu, Tianbao Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6266 - 6269

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  3

DownStream  2

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(2,3-Difluoro-6-nitrophenyl)acetic acid

 (2,3-Difluoro-6-nitrophenyl)acetic acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: The English name of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is 2-(2,3-Difluoro-6-nitrophenyl)acetic acid.
Q: What English synonyms does 2-(2,3-Difluoro-6-nitrophenyl)acetic acid have?
A: English synonyms of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid: (2,3-Difluoro-6-nitrophenyl)acetic acid.
Q: What is the molecular weight of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: Molecular weight of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is 217.126.
Q: What are the upstream materials of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: Related upstream materials(CAS) of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid: 145689-41-4;996-82-7;771-69-7.
Q: What are the downstream products of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: Related downstream products(CAS) of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid: 932373-72-3;914348-35-9.
Q: What is the molecular formula of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: Molecular formula of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is C8H5F2NO4.
Q: What is the SMILES notation of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: SMILES notation of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is O=C(O)Cc1c([N+](=O)[O-])ccc(F)c1F.
Q: What is the InChIKey of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: InChIKey of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is KZNVCGPCWKYPKD-UHFFFAOYSA-N.
Q: What is the CAS number of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: CAS number of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is 141428-47-9.
Q: What is the polar surface area (PSA) of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid?
A: Polar surface area (PSA) of 2-(2,3-Difluoro-6-nitrophenyl)acetic acid is 83.12000.

 (2,3-Difluoro-6-nitrophenyl)acetic acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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