Lapatinib metabolite M6

Modify Date: 2025-09-09 16:38:09

Lapatinib metabolite M6 Structure
Lapatinib metabolite M6 structure
Common Name Lapatinib metabolite M6
CAS Number 1415561-66-8 Molecular Weight 595.0
Density N/A Boiling Point N/A
Molecular Formula C29H24ClFN4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Lapatinib metabolite M6

 Chemical & Physical Properties

Molecular Formula C29H24ClFN4O5S
Molecular Weight 595.0
InChIKey PBJRBJIUNALOPK-VOEWZCDUSA-N
SMILES CS(=O)(=O)CCN(O)C=c1ccc(=c2ccc3c(c2)C(=Nc2ccc(OCc4cccc(F)c4)c(Cl)c2)N=CN=3)o1

 Lapatinib metabolite M6Bioassay

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Name: Activity of recombinant CYP3A5 (unknown origin) assessed as compound formation treate...
Source: ChEMBL
Target: Cytochrome P450 3A5
External Id: CHEMBL3531377
Name: Drug level in human liver microsomes treated with lapatinib at 50 uM by LC/MS/MS anal...
Source: ChEMBL
Target: Liver microsome
External Id: CHEMBL3527791
Name: Activity of recombinant CYP3A4 (unknown origin) assessed as compound formation treate...
Source: ChEMBL
Target: Cytochrome P450 3A4
External Id: CHEMBL3527792
Name: Activity of recombinant CYP3A5 (unknown origin) assessed as compound formation treate...
Source: ChEMBL
Target: Cytochrome P450 3A5
External Id: CHEMBL3531386
Name: Drug level in human liver microsomes treated with lapatinib at 50 uM for 30 mins afte...
Source: ChEMBL
Target: Liver microsome
External Id: CHEMBL3531384
Name: Activity of recombinant CYP3A4 (unknown origin) assessed as compound formation treate...
Source: ChEMBL
Target: Cytochrome P450 3A4
External Id: CHEMBL3531385
Name: Drug level in healthy human plasma treated with [14C]lapatinib at 250 mg, po administ...
Source: ChEMBL
Target: Plasma
External Id: CHEMBL3536945
Name: Retention time of the compound by LC/MS/MS analysis relative to lapatinib
Source: ChEMBL
Target: N/A
External Id: CHEMBL3529323
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