1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione

Modify Date: 2024-01-02 14:47:40

1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione Structure
1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione structure
Common Name 1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
CAS Number 141684-47-1 Molecular Weight 475.58900
Density 1.4g/cm3 Boiling Point N/A
Molecular Formula C18H29N3O8SSi Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4g/cm3
Molecular Formula C18H29N3O8SSi
Molecular Weight 475.58900
Exact Mass 475.14400
PSA 171.58000
LogP 2.21740
Index of Refraction 1.589

 Synthetic Route

~91%

1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione Structure

1-[(6R,8R,9R)-4...

CAS#:141684-47-1

Literature: Camarasa; Perez-Perez; San-Felix; Balzarini; De Clercq Journal of Medicinal Chemistry, 1992 , vol. 35, # 15 p. 2721 - 2727

~%

1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione Structure

1-[(6R,8R,9R)-4...

CAS#:141684-47-1

Literature: Lobaton, Esther; Rodriguez-Barrios, Fatima; Gago, Federico; Perez-Perez, Maria-Jesus; De Clercq, Erik; Balzarini, Jan; Camarasa, Maria-Jose; Velazquez, Sonsoles Journal of medicinal chemistry, 2002 , vol. 45, # 18 p. 3934 - 3945

~%

1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione Structure

1-[(6R,8R,9R)-4...

CAS#:141684-47-1

Literature: Camarasa; Perez-Perez; San-Felix; Balzarini; De Clercq Journal of Medicinal Chemistry, 1992 , vol. 35, # 15 p. 2721 - 2727

~%

1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione Structure

1-[(6R,8R,9R)-4...

CAS#:141684-47-1

Literature: Camarasa; Perez-Perez; San-Felix; Balzarini; De Clercq Journal of Medicinal Chemistry, 1992 , vol. 35, # 15 p. 2721 - 2727

 Synonyms

2'SilylSpiroT