(7R)-SBP-0636457

(7R)-SBP-0636457 structure	Common Name	(7R)-SBP-0636457
	CAS Number	1422180-61-7	Molecular Weight	456.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (7R)-SBP-0636457

(7R)-SBP-0636457 is the inactive isomer of SBP-0636457 (HY-125378), and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2].

Name	(7R)-SBP-0636457

Description	(7R)-SBP-0636457 is the inactive isomer of SBP-0636457 (HY-125378), and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Finlay D, et, al. Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. Mol Cancer Ther. 2014 Jan; 13(1): 5-15. [2]. Finlay D, et, al. Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. F1000Res. 2017 Apr 27; 6:587.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Finlay D, et, al. Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. Mol Cancer Ther. 2014 Jan; 13(1): 5-15.

[2]. Finlay D, et, al. Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. F1000Res. 2017 Apr 27; 6:587.

Molecular Formula	C₂₅H₃₆N₄O₄
Molecular Weight	456.58
InChIKey	PBGOFGSVVXGJCA-YSCIFQABSA-N
SMILES	CNC(C)C(=O)NC1CCOC2CC(C)(C)C(C(=O)NC3CCCc4ccccc43)N2C1=O

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (7R)-SBP-0636457
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

(7R)-SBP-0636457 suppliers

Price: ￥8570/5 mg

Reference only. check more (7R)-SBP-0636457 price

(7R)-SBP-0636457

Use of (7R)-SBP-0636457

Names

(7R)-SBP-0636457 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.