Autocamtide-3

Modify Date: 2024-04-11 15:11:25

Autocamtide-3 structure	Common Name	Autocamtide-3
	CAS Number	142828-10-2	Molecular Weight	1508.72
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₅H₁₁₃N₂₁O₂₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Autocamtide-3

Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate[1].

Name	Autocamtide-3

Description	Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> CaMK Research Areas >> Neurological Disease
Target	CaMK II
In Vitro	20 μM Autocamtide-3 (H2N-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-COOH), and 5 μL of CaMKII is used in a 50 μL kinase-assay reaction. Autocamtide-3 shows catalytic activity[1].
References	[1]. Mehtap Yilmaz, et al. Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity. Biosci Rep. 2013 Feb 7;33(2):e00024.

Molecular Formula	C₆₅H₁₁₃N₂₁O₂₀
Molecular Weight	1508.72