N1-Methylpseudouridine-5′-triphosphate

Modify Date: 2024-01-11 17:59:29

N1-Methylpseudouridine-5′-triphosphate Structure
N1-Methylpseudouridine-5′-triphosphate structure
 Common Name N1-Methylpseudouridine-5′-triphosphate
CAS Number 1428903-59-6 Molecular Weight 498.17
Density 2.010±0.06 g/cm3 Boiling Point N/A
Molecular Formula C10H17N2O15P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N1-Methylpseudouridine-5′-triphosphate


N1-Methylpseudouridine-5′-triphosphate (N1-Me-Pseudo UTP) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

 Names

Name N1-Methylpseudouridine-5'-triphosphate

 N1-Methylpseudouridine-5′-triphosphate Biological Activity

Description N1-Methylpseudouridine-5′-triphosphate (N1-Me-Pseudo UTP) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
Related Catalog
References

[1]. Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344.

 Chemical & Physical Properties

Density 2.010±0.06 g/cm3
Molecular Formula C10H17N2O15P3
Molecular Weight 498.17
Storage condition -20°C
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