D- erythro MAPP
Modify Date: 2024-01-10 08:54:33
D- erythro MAPP structure
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Common Name | D- erythro MAPP | ||
|---|---|---|---|---|
| CAS Number | 143492-38-0 | Molecular Weight | 361.561 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 536.7±43.0 °C at 760 mmHg | |
| Molecular Formula | C23H39NO2 | Melting Point | 82ºC to 84ºC | |
| MSDS | N/A | Flash Point | 278.4±28.2 °C | |
Use of D- erythro MAPPD-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro[1]. |
| Name | N-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]tetradecanamide |
|---|---|
| Synonym | More Synonyms |
| Description | D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro[1]. |
|---|---|
| Related Catalog | |
| In Vitro | D-erythro-MAPP (D-e-MAPP) reduces the viability of MCF-7 cells in a dose-dependent manner with IC50 value of 4.4 μM, and 15.6 μM, respectively[1]. D-erythro-MAPP (D-e-MAPP) induces G0/G1 arrest in cell cycle progression resulting in growth suppression[2]. Cell Viability Assay[1] Cell Line: Human breast cancer MCF-7 cells. Concentration: 24 h. Incubation Time: 3.13-100 μM. Result: Inhibited cell viability. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 536.7±43.0 °C at 760 mmHg |
| Melting Point | 82ºC to 84ºC |
| Molecular Formula | C23H39NO2 |
| Molecular Weight | 361.561 |
| Flash Point | 278.4±28.2 °C |
| Exact Mass | 361.298065 |
| PSA | 49.33000 |
| LogP | 6.92 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.502 |
| N-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]tetradecanamide |
| Tetradecanamide, N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]- |
| MAPP,D-erythro |
| N-[(1S,2R)-1-Hydroxy-1-phenyl-2-propanyl]tetradecanamide |
| D-erythro-MAPP |