N6-Ethyladenosine

Modify Date: 2024-01-10 02:17:00

N6-Ethyladenosine Structure
N6-Ethyladenosine structure
Common Name N6-Ethyladenosine
CAS Number 14357-08-5 Molecular Weight 295.29
Density 1.76g/cm3 Boiling Point 642.9ºC at 760mmHg
Molecular Formula C12H17N5O4 Melting Point N/A
MSDS N/A Flash Point 342.6ºC

 Use of N6-Ethyladenosine


N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1].

 Names

Name 2-[6-(ethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

 N6-Ethyladenosine Biological Activity

Description N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1].
Related Catalog
Target

Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)[1]

In Vitro N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
References

[1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.

 Chemical & Physical Properties

Density 1.76g/cm3
Boiling Point 642.9ºC at 760mmHg
Molecular Formula C12H17N5O4
Molecular Weight 295.29
Flash Point 342.6ºC
Exact Mass 295.12800
PSA 125.55000
Vapour Pressure 2.09E-17mmHg at 25°C
Index of Refraction 1.778
Storage condition 2-8℃

 Synonyms

N6-dimethylaminomethylene-O2',O3'-isopropylidene-adenosine
N6-Dimethylaminomethylen-2'-desoxy-adenosin
N6-dimethylaminomethylene-2',3'-O-isopropyldeneadenosine
N6-ethyl-adenosine
6-N-Ethyladenoside
N6-Ethyladenosine