AR234960

Modify Date: 2025-08-27 10:25:11

AR234960 Structure
AR234960 structure
Common Name AR234960
CAS Number 1436426-86-6 Molecular Weight 555.62
Density N/A Boiling Point N/A
Molecular Formula C27H30FN5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AR234960


AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac fibroblasts[1].

 Names

Name AR234960

 AR234960 Biological Activity

Description AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac fibroblasts[1].
Related Catalog
Target

MAS[1].

References

[1]. Chatterjee A, et al. Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts. PLoS One. 2017 Dec 29;12(12):e0190217.

 Chemical & Physical Properties

Molecular Formula C27H30FN5O5S
Molecular Weight 555.62
InChIKey TUSCHIFEASZBBF-UHFFFAOYSA-N
SMILES COc1cc([N+](=O)[O-])ccc1S(=O)(=O)N1CC(CN2CCN(c3ccccn3)CC2)C(c2cccc(F)c2)C1

 AR234960Bioassay

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Name: Human MAS1 (Class A Orphans)
Source: IUPHAR-DB
Target: MAS1 (Class A Orphans) [Homo sapiens]
External Id: 150_Human
Name: Rat MAS1 (Class A Orphans)
Source: IUPHAR-DB
Target: MAS1 (Class A Orphans) [Rattus norvegicus]
External Id: 150_Rat
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